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A premarital screening is a crucial health assessment for couples that are planning to get married, as this screening helps couples to identify potential health problems and risks for themselves and also their offspring. Premarital screening usually includes screening for infectious diseases and genetic disorders. Infectious diseases and transmissible diseases screening is important to avoid any risk of transmitting any diseases such as Hepatitis B, HIV, HCV and other sexually transmitted diseases to each other and their children. Genetic disorders screening is vital to identify carriers of genetic disorders which may affect their children like Thalassemia, Haemophilia and Sickle Cell Disease.